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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMAD1 All Species: 29.09
Human Site: S209 Identified Species: 64
UniProt: Q15797 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15797 NP_001003688.1 465 52260 S209 T Y P H S P T S S D P G S P F
Chimpanzee Pan troglodytes XP_001148109 465 52214 S209 T Y P H S P T S S D P G S P F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532681 465 52174 S209 T Y P H S P T S S D P G S P F
Cat Felis silvestris
Mouse Mus musculus P70340 465 52100 S209 T Y P H S P T S S D P G S P F
Rat Rattus norvegicus P97588 468 52695 P212 H S P T S S D P G S P F Q M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510186 465 52277 S209 T Y P H S P T S S D P G S P F
Chicken Gallus gallus Q56I99 465 52210 S209 Y P S S P A S S G P S S P F Q
Frog Xenopus laevis NP_001079973 464 52355 S208 T Y P H S P A S S D P G S P F
Zebra Danio Brachydanio rerio Q9I8V2 472 53048 S216 T F P H S P S S S D P G S P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42003 455 50486 S199 S L S T S N T S V G S P S S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q02330 418 47907 Q169 M S G S R M P Q N V N M A N V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 99.3 N.A. 98.7 97.4 N.A. 98.9 90.3 95.6 88.5 N.A. 75 N.A. 51.6 N.A.
Protein Similarity: 100 100 N.A. 99.5 N.A. 99.3 97.8 N.A. 99.3 92.4 97.4 93.8 N.A. 83.6 N.A. 63.8 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 20 N.A. 100 6.6 93.3 86.6 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 20 N.A. 100 13.3 93.3 100 N.A. 33.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 64 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 10 0 10 64 % F
% Gly: 0 0 10 0 0 0 0 0 19 10 0 64 0 0 0 % G
% His: 10 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 10 0 0 10 0 % N
% Pro: 0 10 73 0 10 64 10 10 0 10 73 10 10 64 10 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 19 19 19 82 10 19 82 64 10 19 10 73 10 0 % S
% Thr: 64 0 0 19 0 0 55 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _